pegfp c1 aβ 1 42 plasmid Search Results


pegfp c1 aβ 1 42 plasmid  (Addgene inc)
91
Addgene inc pegfp c1 aβ 1 42 plasmid
Pegfp C1 Aβ 1 42 Plasmid, supplied by Addgene inc, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
pegfp c1 aβ 1 42 plasmid - by Bioz Stars, 2026-07
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pegfp c1 aβ 1 42  (Addgene inc)
94
Addgene inc pegfp c1 aβ 1 42
Pegfp C1 Aβ 1 42, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/pmc10698508-393-10-14?v=Addgene+inc
Average 94 stars, based on 1 article reviews
pegfp c1 aβ 1 42 - by Bioz Stars, 2026-07
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hek293 cells  (Addgene inc)
93
Addgene inc hek293 cells
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Hek293 Cells, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/pmc10698508-393-0-14?v=Addgene+inc
Average 93 stars, based on 1 article reviews
hek293 cells - by Bioz Stars, 2026-07
93/100 stars
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n a recombinant ttr m v30m sasaki  (Peptide Institute)
86
Peptide Institute n a recombinant ttr m v30m sasaki
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
N A Recombinant Ttr M V30m Sasaki, supplied by Peptide Institute, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/10__1016_slash_j__isci__2025__114170-501-157-188?v=Peptide+Institute
Average 86 stars, based on 1 article reviews
n a recombinant ttr m v30m sasaki - by Bioz Stars, 2026-07
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recombinant proteins methyl gallate tokyo chemical industry  (Tokyo Chemical Industry)
86
Tokyo Chemical Industry recombinant proteins methyl gallate tokyo chemical industry
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Recombinant Proteins Methyl Gallate Tokyo Chemical Industry, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/10__1016_slash_j__isci__2025__114170-501-35-39?v=Tokyo+Chemical+Industry
Average 86 stars, based on 1 article reviews
recombinant proteins methyl gallate tokyo chemical industry - by Bioz Stars, 2026-07
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n a 1 1 1 3 3 3 hexafluoro 2 propanol hfip merck milliporesigma  (Merck & Co)
86
Merck & Co n a 1 1 1 3 3 3 hexafluoro 2 propanol hfip merck milliporesigma
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
N A 1 1 1 3 3 3 Hexafluoro 2 Propanol Hfip Merck Milliporesigma, supplied by Merck & Co, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/10__1016_slash_j__isci__2025__114170-501-133-136?v=Merck+%26+Co
Average 86 stars, based on 1 article reviews
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β sitosterol nacalai tesque  (Nacalai)
86
Nacalai β sitosterol nacalai tesque
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
β Sitosterol Nacalai Tesque, supplied by Nacalai, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/10__1016_slash_j__isci__2025__114170-501-68-69?v=Nacalai
Average 86 stars, based on 1 article reviews
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pegfp c1 aβ1 42 plasmid  (Addgene inc)
93
Addgene inc pegfp c1 aβ1 42 plasmid
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Pegfp C1 Aβ1 42 Plasmid, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+a%CE%B2+1+42+plasmid/pm35462559-50-1-6?v=Addgene+inc
Average 93 stars, based on 1 article reviews
pegfp c1 aβ1 42 plasmid - by Bioz Stars, 2026-07
93/100 stars
  Buy from Supplier

Image Search Results


A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in HEK293 cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.

Journal: Molecular Systems Biology

Article Title: A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

doi: 10.15252/msb.202311801

Figure Lengend Snippet: A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in HEK293 cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.

Article Snippet: HEK293 cells having 70–80% cell density were transiently transfected with pEGFP‐C1‐Aβ 1‐42 , pEGFP‐Htt‐exon1‐Q74 (Addgene #40262), pEGFP‐Ataxin1‐52Q (Addgene #32492), or pEGFP‐C1‐Ataxin3‐Q84 (Addgene #22123) DNA using Lipofectamine 2000 (Invitrogen, CA, USA) following the manufacturer's instructions.

Techniques:

Journal: Molecular Systems Biology

Article Title: A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

doi: 10.15252/msb.202311801

Figure Lengend Snippet:

Article Snippet: HEK293 cells having 70–80% cell density were transiently transfected with pEGFP‐C1‐Aβ 1‐42 , pEGFP‐Htt‐exon1‐Q74 (Addgene #40262), pEGFP‐Ataxin1‐52Q (Addgene #32492), or pEGFP‐C1‐Ataxin3‐Q84 (Addgene #22123) DNA using Lipofectamine 2000 (Invitrogen, CA, USA) following the manufacturer's instructions.

Techniques: Over Expression, Plasmid Preparation, Construct